The hamster as an experimental animal for the study of influenza
Identifieur interne : 002B43 ( Main/Exploration ); précédent : 002B42; suivant : 002B44The hamster as an experimental animal for the study of influenza
Auteurs : R. Jennings [Royaume-Uni] ; J. P. Phair [Royaume-Uni] ; M. D. Denton [Royaume-Uni] ; C. W. Potter [Royaume-Uni]Source :
- Medical Microbiology and Immunology [ 0300-8584 ] ; 1976-12-01.
English descriptors
- Teeft :
- Adoptive, Adoptive transfer, Adoptive transfer experiments, Antibody response, Challenge infection, Hamster, Hamsters inoculated, Immune, Immune response, Immune spleen cells, Immunol, Infection, Influenza, Influenza virus, Influenza virus antigens, Influenza virus infection, Influenza viruses, Inoculated, Jennings, Macrophage, Normal hamsters, Normal spleen cells, Present studies, Recipient hamsters, Serum antibody, Specific antibody, Spleen, Spleen cell transfer, Spleen cells, Virus, Virus infections.
Abstract
Abstract: Hamsters previously infected by influenza viruses, have been shown to have a cell-mediated immune response, as measured by the macrophage migration inhibition test. The participation of spleen cells in the protection of recipients against homologous influenza virus infection was also demonstrated using adoptive transfer experiments. However, the protection achieved by spleen cell transfer was marginal and not observed in every animal. The time at which the spleen cells were transferred following infection, and their number, affected the outcome. Evidence suggesting that transferred spleen cells protected recipient hamsters through specific antibody is presented.
Url:
DOI: 10.1007/BF02121001
Affiliations:
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Jennings</name><affiliation wicri:level="2"><country>Royaume-Uni</country><placeName><region type="country">Angleterre</region></placeName><wicri:cityArea>Academic Division of Pathology, Department of Virology, University of Sheffield Medical School, S10 2RX, Sheffield</wicri:cityArea></affiliation></author><author><name sortKey="Phair, J P" sort="Phair, J P" uniqKey="Phair J" first="J. P." last="Phair">J. P. Phair</name><affiliation wicri:level="2"><country>Royaume-Uni</country><placeName><region type="country">Angleterre</region></placeName><wicri:cityArea>Academic Division of Pathology, Department of Virology, University of Sheffield Medical School, S10 2RX, Sheffield</wicri:cityArea></affiliation></author><author><name sortKey="Denton, M D" sort="Denton, M D" uniqKey="Denton M" first="M. D." last="Denton">M. D. 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Potter</name><affiliation wicri:level="2"><country>Royaume-Uni</country><placeName><region type="country">Angleterre</region></placeName><wicri:cityArea>Academic Division of Pathology, Department of Virology, University of Sheffield Medical School, S10 2RX, Sheffield</wicri:cityArea></affiliation></author></analytic><monogr></monogr><series><title level="j">Medical Microbiology and Immunology</title><title level="j" type="abbrev">Med Microbiol Immunol</title><idno type="ISSN">0300-8584</idno><idno type="eISSN">1432-1831</idno><imprint><publisher>Springer-Verlag</publisher><pubPlace>Berlin/Heidelberg</pubPlace><date type="published" when="1976-12-01">1976-12-01</date><biblScope unit="volume">162</biblScope><biblScope unit="issue">3-4</biblScope><biblScope unit="page" from="227">227</biblScope><biblScope unit="page" to="237">237</biblScope></imprint><idno type="ISSN">0300-8584</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0300-8584</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="Teeft" xml:lang="en"><term>Adoptive</term><term>Adoptive transfer</term><term>Adoptive transfer experiments</term><term>Antibody response</term><term>Challenge infection</term><term>Hamster</term><term>Hamsters inoculated</term><term>Immune</term><term>Immune response</term><term>Immune spleen cells</term><term>Immunol</term><term>Infection</term><term>Influenza</term><term>Influenza virus</term><term>Influenza virus antigens</term><term>Influenza virus infection</term><term>Influenza viruses</term><term>Inoculated</term><term>Jennings</term><term>Macrophage</term><term>Normal hamsters</term><term>Normal spleen cells</term><term>Present studies</term><term>Recipient hamsters</term><term>Serum antibody</term><term>Specific antibody</term><term>Spleen</term><term>Spleen cell transfer</term><term>Spleen cells</term><term>Virus</term><term>Virus infections</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Abstract: Hamsters previously infected by influenza viruses, have been shown to have a cell-mediated immune response, as measured by the macrophage migration inhibition test. The participation of spleen cells in the protection of recipients against homologous influenza virus infection was also demonstrated using adoptive transfer experiments. However, the protection achieved by spleen cell transfer was marginal and not observed in every animal. The time at which the spleen cells were transferred following infection, and their number, affected the outcome. Evidence suggesting that transferred spleen cells protected recipient hamsters through specific antibody is presented.</div></front></TEI><affiliations><list><country><li>Royaume-Uni</li></country><region><li>Angleterre</li></region></list><tree><country name="Royaume-Uni"><region name="Angleterre"><name sortKey="Jennings, R" sort="Jennings, R" uniqKey="Jennings R" first="R." last="Jennings">R. Jennings</name></region><name sortKey="Denton, M D" sort="Denton, M D" uniqKey="Denton M" first="M. D." last="Denton">M. D. Denton</name><name sortKey="Phair, J P" sort="Phair, J P" uniqKey="Phair J" first="J. P." last="Phair">J. P. Phair</name><name sortKey="Potter, C W" sort="Potter, C W" uniqKey="Potter C" first="C. W." last="Potter">C. W. Potter</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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